Knowledge and Determinants of Vaccine Hesitancy Among Residents of Ifako Ijaiye LGA, Lagos State
Main Article Content
Abstract
Vaccine hesitancy poses a significant challenge to public health efforts in Nigeria. However, vaccine hesitancy is not a matter of chance; such an attitude is shaped by a myriad of factors, among which the knowledge of vaccines plays a complex and sometimes paradoxical role in shaping attitudes toward vaccine uptake. Thus, this study assessed the knowledge and determinants of vaccine hesitancy among residents of Ifako-Ijaiye LGA, Lagos State. The study adopts a cross-sectional survey design, and a total of 427 respondents were selected through a multi-stage sampling. Data was collected using a well-structured questionnaire over a period of three months (June-August, 2025). The retrieved questionnaire was analysed using Statistical Package for Social Sciences (SPSS) version 25.0, and the p-value was set at <0.05. The findings of the study showed that two-thirds of the respondents had good knowledge of vaccination, and 77.4% of the respondents noted that vaccines are easily accessible in their area. Prevalence rate of vaccine hesitancy observed in Ifako-Ijaiye LGA was 14.30%. Factors such as trust in healthcare institutions, knowledge of vaccinations, and occupation were found to be significantly associated with vaccine hesitancy. The study concludes that vaccine hesitancy is not merely a product of insufficient knowledge but arises from the interplay of religious identity, educational background, economic conditions, and most critically, levels of trust in vaccine safety.
Downloads
Article Details
Section

This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
References
1.World Health Organization (WHO). (2024). Immunization Coverage. [Fact sheet]. Retrieved from https://www.who.int/news-room/fact-sheets/detail/immunization-coverage
2.Larson, H. J., Jarrett, C., Eckersberger, E., Smith, D. M. D., & Paterson, P. (2014). Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature, 2007–2012. Vaccine, 32(19), 2150–2159. https://doi.org/10.1016/j.vaccine.2014.01.081
3.MacDonald, N. E., & SAGE Working Group on Vaccine Hesitancy. (2015). Vaccine hesitancy: Definition, scope and determinants. Vaccine, 33(34), 4161–4164. https://doi.org/10.1016/j.vaccine.2015.04.036
4.Nigeria Centre for Disease Control and Prevention (NCDC). (2023). Diphtheria Situation Report. Retrieved from https://ncdc.gov.ng/diseases/sitreps/
5.World Health Organization (WHO). (2023). Measles – Nigeria. Disease Outbreak News. Retrieved from https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON476
6.Gulumbe, B. H., Danlami, M. B., Yusuf, A. B., Shehu, A., & Chidiebere, O. (2024). Vaccine hesitancy under the lens: Nigeria’s struggle against the worst diphtheria outbreak in decades. Therapeutic Advances in Infectious Disease, 11. https://doi.org/10.1177/20499361241242218
7.Lagos Ministry of Health, (2023).https://www.premiumtimesng.com/news/top-news/752735-lagos-has-1800-private-362-public-healthcare-facilities-commissioner.html?tztc=1
8.Voo, J. Y. H., Lean, Q. Y., Ming, L. C., Hanafiah, N. H., & Al-Worafi, Y. M. (2021). Vaccine Knowledge, Awareness and Hesitancy: A Cross Sectional Survey among Parents Residing at Sandakan District, Sabah. Vaccines, 9(11), 1348. https://doi.org/10.3390/vaccines9111348
9.Ibekwe, R., Nnabuihe, E., & Ukoha, K. (2024). Awareness and Determinants of COVID-19 Vaccine Acceptance in Nigeria: A Population-Based Study. Journal of Epidemiology and Global Health, 14(1), 45-55. https://doi.org/10.1007/s44197-024-00230-8
10.Betsch, C., Wieler, L. H., & Habersaat, K. (2020). Monitoring behavioural insights related to COVID-19. The Lancet, 395(10232), 1255–1256. https://doi.org/10.1016/S0140-6736(20)30729-7
11.Sule, S. S., Onayade, A. A., Abayomi, O. O., & Fatusi, A. O. (2020). Knowledge, attitude and practice of childhood immunization among mothers in a primary health care centre in Lagos, Nigeria. Nigerian Journal of Paediatrics, 47(2), 45-51. https://doi.org/10.4314/njp.v47i2.1
12.Omomala, O. O., & Olorunsaiye, C. Z. (2020). Knowledge and uptake of childhood immunization among mothers in Ilorin, Nigeria. Journal of Public Health in Africa, 11(1), 1156. https://doi.org/10.4081/jphia.2020.1156
13.Rozario, S., Omer, M. D., Gallagher, K., Aregay, A. K., Sheikh, A., & Mohamoud, A. S. (2016). The Polio Communication Network's contribution to the polio outbreak response in Ethiopia’s Somali Region, 2013–2015. Global Health Communication, 2(1), 39–49. https://doi.org/10.1080/23762004.2017.1330604
14.Dubé, È., Ward, J. K., Verger, P., & MacDonald, N. E. (2021). Vaccine hesitancy, acceptance, and anti-vaccination: trends and future prospects for public health. Annual Review of Public Health, 42, 175–191. https://doi.org/10.1146/annurev-publhealth-090419-102240
15.Adebisi, Y. A., Alaran, A. J., Bolarinwa, O. A., Akande-Sholabi, W., & Lucero-Prisno, D. E. (2021). When it is available, will we take it? Public perception of hypothetical COVID-19 vaccine in Nigeria. Pan African Medical Journal, 38(1), 230. https://doi.org/10.11604/pamj.2021.38.230.27325
16.Oduwole, E. O., Pienaar, E. D., Mahomed, H., & Wiysonge, C. S. (2021). Current tools available for investigating vaccine hesitancy. Cochrane Database of Systematic Reviews, 2021(3), CD013493. https://doi.org/10.1002/14651858.CD013493.pub2
17.Jegede, A. S. (2007). What led to the Nigerian boycott of the polio vaccination campaign? PLoS Medicine, 4(3),e73. https://doi.org/10.1371/journal.pmed.0040073
18.Olagoke, A. A., Olagoke, O. O., & Hughes, A. M. (2021). Intention to vaccinate against the novel 2019 coronavirus disease: The role of health locus of control and religiosity. Journal of Religion and Health, 60(1), 65–80. https://doi.org/10.1007/s10943-020-01090-9
19.Bish, A., & Michie, S. (2010). Demographic and attitudinal determinants of protective behaviours during a pandemic: A review. British Journal of Health Psychology, 15(4), 797–824. https://doi.org/10.1348/135910710X485826
20.Wang, Y., McKee, M., Torbica, A., & Stuckler, D. (2019). Systematic Literature Review on the Spread of Health-related Misinformation on Social Media. Social Science & Medicine, 240, 112552. https://doi.org/10.1016/j.socscimed.2019.112552
21.Betsch, C., Schmid, P., Heinemeier, D., Korn, L., Holtmann, C., & Böhm, R. (2018). Beyond confidence: Development of a measure assessing the 5C psychological antecedents of vaccination. PLOS ONE, 13(12), e0208601. https://doi.org/10.1371/journal.pone.0208601