Al-Hikmah University Journal

Blood storage lesion is a rapidly growing area of biomedical research which leaves several questions unanswered. This study assessed blood donation frequency, as it affects hematological and biochemical parameters among different categories of blood donors longitudinally over a period of 35 days at 2-60C. Ethically approved cross-sectional research involving family (n=30), remunerated donors: mild (n=30), moderate (n=30) and high frequency (n=30). One hundred milliliters (100 mL) of well-mixed blood was transferred into the satellite bag from 450mls of blood from different categories of blood donors. Haemogram, plasma Ferritin, Erythropoietin (EPO), 2, 3-diphosphoglycerate, Sodium (Na+) and Potassium (K+) assessed at 0, 7, 14, 21, 28 and 35 days of storage were analyzed. This study revealed acceptable normal high values in Haemogram, erythropoietin and ferritin in family donors while Remunerated donors had mild to moderate anemia, high total WBC count, higher platelet count, a very low ferritin content, low red cell indices, high EPO, hypernatremia, hyperkalaemia and high 2, 3. Diphosphoglycerate (2, 3, DPG). Significant iron deficiency anemia and electrolyte imbalance among moderate to high frequent blood donors.